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Background
Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed: 16186509). Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.
Product overview
Product Name
Protein Sel-1 Homolog 1
Code
E6004Hu
Assay type
Sandwich
Size
96 test
Sensitivity
4.47ng/L
Reactivity
Human
Detection range
4.47ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Protein sel-1 homolog 1;SEL1L;Sel-1L;Suppressor of lin-12-like protein 1
