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Background
May play a role in cell differentiation, proliferation and apoptosis (PubMed: 24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed: 20818439).
Product overview
Product Name
Prominin-1
Code
E5935Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.051ng/mL
Reactivity
Human
Detection range
0.051ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
Antigen AC133;CD antigen CD133;PROM 1;PROM1;Prominin-1;Prominin-like protein 1
