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Human Plexin A2, PLXNA2 ELISA Kit

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BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.

Background

Coreceptor for SEMA3A and SEMA6A. Necessary for signaling by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).

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