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Background
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway. [Isoform 1]: Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. [Isoform 2]: Is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
Product overview
Product Name
Peroxisomal Acyl-Coenzyme A Oxidase 1
Code
E4164hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.78ng/L
Reactivity
Human
Detection range
9.78ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ACOX 1;ACOX1;AOX;Palmitoyl-CoA oxidase;Peroxisomal acyl-CoA oxidase 1, A chain;Peroxisomal acyl-CoA oxidase 1, B chain;Peroxisomal acyl-CoA oxidase 1, C chain;Peroxisomal acyl-coenzyme A oxidase 1;SCOX;Straight-chain acyl-CoA oxidase
