Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P (PubMed:23934110) (Probable).
Plays a role in negative regulation of lipid biosynthesis (PubMed:19554302).
Negatively regulates APOB secretion from hepatocytes (PubMed:19554302, PubMed:22906437).
Binds cholesterol and acidic phospholipids (PubMed:22906437).
Also binds 25-hydroxycholesterol (PubMed:17428193).
Binds phosphatidylserine (PubMed:23934110).
Related Resources