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Background
Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development (PubMed: 28381549).
Product overview
Product Name
Nuclear Receptor-Interacting Protein 1
Code
E6857Hu
Assay type
Sandwich
Size
96 test
Sensitivity
11.63ng/L
Reactivity
Human
Detection range
11.63ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
NRIP 1;NRIP1;Nuclear factor RIP140;Nuclear receptor-interacting protein 1;Receptor-interacting protein 140