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Background
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed: 10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).
Product overview
Product Name
Nuclear Factor of Activated T-Cells, Cytoplasmic 1