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Background
Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed: 15107016). The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria (By similarity).
Product overview
Product Name
Nlr Family, Card Domain Containing 4
Code
E3582Hu
Assay type
Sandwich
Size
96 test
Sensitivity
5.15ng/L
Reactivity
Human
Detection range
5.15ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CARD, LRR, and NACHT-containing protein;Caspase recruitment domain-containing protein 12;Clan protein;Ice protease-activating factor;Ipaf;NLR family CARD domain-containing protein 4;NLRC 4;NLRC4
