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Background
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival (PubMed: 31536960). Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity). Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways (By similarity). Neurotrophic activity is enhanced by binding to heme (By similarity). Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity).
Product overview
Product Name
Neudesin
Code
E4258hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.026ng/ml
Reactivity
Human
Detection range
0.026ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Cell immortalization-related protein 2;NENF;Neudesin;Neuron-derived neurotrophic factor;Protein GIG47;Secreted protein of unknown function;SPUF protein
