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Background
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Product overview
Product Name
leukocyte immunoglobulin-like receptor subfamily B member 4
Code
E0240Hu
Assay type
Sandwich
Size
96 test
Sensitivity
3.22ng/L
Reactivity
Human
Detection range
3.22ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD85k;CD85 antigen-like family member K;CD85K;ILT3;ILT-3;Immunoglobulin-like transcript 3;Leukocyte immunoglobulin-like receptor 5;Leukocyte immunoglobulin-like receptor subfamily B member 4;LILRB4;LIR5;LIR-5;Monocyte inhibitory receptor HM18
