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Background
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed: 20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).
Product overview
Product Name
Kinesin-1 Heavy Chain
Code
E4204hu
Assay type
Sandwich
Size
96 test
Sensitivity
2.55ng/ml
Reactivity
Human
Detection range
2.55ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Conventional kinesin heavy chain;KIF5B;Kinesin-1 heavy chain;Ubiquitous kinesin heavy chain;UKHC
