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Background
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity).
Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as an inhibitor of PPP1C.
Product overview
Product Name
Inactive phospholipase C-like protein 1
Code
E5460Hu
Assay type
Sandwich
Size
96 test
Sensitivity
10.12ng/L
Reactivity
Human
Detection range
10.12ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Inactive phospholipase C-like protein 1;Phospholipase C-deleted in lung carcinoma;Phospholipase C-related but catalytically inactive protein;PLCE;PLCL;PLCL1;PLC-L1;PLDL1;PPP1R127;PRIP
