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Background
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Product overview
Product Name
ICOS ligand
Code
E5446Hu
Assay type
Sandwich
Size
96 test
Sensitivity
25.34ng/L
Reactivity
Human
Detection range
25.34ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
B7 homolog 2;B7h;B7H2;B7-H2;B7-like protein Gl50;B7-related protein 1;B7RP1;B7RP-1;CD antigen CD275;CD275;GL50;ICOS ligand;ICOS-L;ICOSLG;LICOS
