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Human Homeobox Protein Nkx-2.5, NKX2-5 ELISA Kit

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BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.

Background

Transcription factor required for the development of the heart and the spleen (PubMed: 22560297). During heart development, acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed: 22849347, PubMed: 26926761). Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression (PubMed: 22560297).

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