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Background
Transcription factor required for the development of the heart and the spleen (PubMed: 22560297). During heart development, acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity). Binds to the core DNA motif of NPPA promoter (PubMed: 22849347, PubMed: 26926761). Together with PBX1, required for spleen development through a mechanism that involves CDKN2B repression (PubMed: 22560297).
Product overview
Product Name
Homeobox Protein Nkx-2.5
Code
E5433Hu
Assay type
Sandwich
Size
96 test
Sensitivity
8.01ng/L
Reactivity
Human
Detection range
8.01ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Cardiac-specific homeobox;Homeobox protein CSX;Homeobox protein NK-2 homolog E;Homeobox protein Nkx-2.5;NKX 2 5;NKX2 5;NKX2-5