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Background
Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16289116, PubMed:28827405).
Could enhance presenilin-mediated amyloid-beta protein 40 generation. Binds to ubiquilins and this interaction is required for efficient degradation of CD3D via the ERAD pathway (PubMed:18307982).
Product overview
Product Name
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein
Code
E5436Hu
Assay type
Sandwich
Size
96 test
Sensitivity
5.16ng/L
Reactivity
Human
Detection range
5.16ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
HERP;HERPUD1;Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein;Methyl methanesulfonate;Mif1;MMF-inducible fragment protein 1;SUP
