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Background
Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
Product overview
Product Name
Fibroblast Growth Factor-Binding Protein 3
Code
E6500Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.015ng/ml
Reactivity
Human
Detection range
0.015ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
FGF-binding protein 3;FGFBP 3;FGFBP3;FGFBP-3;FGF-BP3;Fibroblast growth factor-binding protein 3