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Background
Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity). The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (PubMed: 17398095). Involved in neurite growth (By similarity).
Product overview
Product Name
Cytohesin-2
Code
E5162Hu
Assay type
Sandwich
Size
96 test
Sensitivity
3.04ng/L
Reactivity
Human
Detection range
3.04ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
ARF exchange factor;ARF nucleotide-binding site opener;CYTH 2;CYTH2;Cytohesin-2;PH, SEC7 and coiled-coil domain-containing protein 2;Protein ARNO
