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Background
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore.
Product overview
Product Name
Centromere Protein K
Code
E5030Hu
Assay type
Sandwich
Size
96 test
Sensitivity
6.95ng/L
Reactivity
Human
Detection range
6.95ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CENPK;CENP-K;Centromere protein K;Interphase centromere complex protein 37;p33;Protein AF-5alpha