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Human Cd320 Antigen, CD320 ELISA Kit

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BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.

Background

Receptor for transcobalamin saturated with cobalamin (TCbl) (PubMed: 18779389). Plays an important role in cobalamin uptake (PubMed: 18779389, PubMed: 20524213). Plasma membrane protein that is expressed on follicular dendritic cells (FDC) and mediates interaction with germinal center B cells (PubMed: 10727470). Functions as costimulator to promote B cell responses to antigenic stimuli; promotes B cell differentiation and proliferation (PubMed: 10727470, PubMed: 11418631). Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (PubMed: 11418631). CD320 augments the proliferation of PC precursors generated by IL-10 (PubMed: 11418631).

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