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Background
Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation (By similarity). Antagonizes the function of BMP7 and may thus play an important role in the embryonic bone formation. Shows no inhibitory effect on the inducing activity of BMP2. Plays a role during anterior segment eye development (By similarity).
Product overview
Product Name
Chordin-Like Protein 1
Code
E1937Mo
Assay type
Sandwich
Size
96 test
Sensitivity
5.15ng/L
Reactivity
Mouse
Detection range
5.15ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
Chordin-like protein 1;CHRDL 1;CHRDL1;Neuralin-1;Neurogenesin-1;Ventroptin
