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Background
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. [Isoform eNOS13C]: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
Product overview
Product Name
Tek Tyrosine Kinase, Endothelial
Code
E7308Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.23ng/ml
Reactivity
Human
Detection range
0.23ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
cNOS;Constitutive NOS;EC-NOS;Endothelial NOS;eNOS;Nitric oxide Synthase, endothelial;NOS 3;NOS type III;NOS3;NOSIII