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Background
Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
Product overview
Product Name
Microtubule-Associated Protein 1B
Code
E4782Hu
Assay type
Sandwich
Size
96 test
Sensitivity
7.58ng/L
Reactivity
Human
Detection range
7.58ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
MAP1 light chain LC1;MAP1B;MAP-1B;MAP1B heavy chain;Microtubule-associated protein 1B
