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Background
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Product overview
Product Name
Chordin-Like Protein 1
Code
E5045Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.027ng/ml
Reactivity
Human
Detection range
0.027ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Chordin-like protein 1;CHRDL 1;CHRDL1;Neuralin-1;Neurogenesin-1;Ventroptin