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Background
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
Product overview
Product Name
Tnf Receptor-Associated Factor 5
Code
E6498Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.011ng/ml
Reactivity
Human
Detection range
0.011ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
RING finger protein 84;TNF receptor-associated factor 5;TRAF 5;TRAF5