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Human Low Affinity Immunoglobulin Gamma Fc Region Receptor 3-B, FCGR3B ELISA Kit, E5598Hu

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Background

Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.

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