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Background
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Product overview
Product Name
Low affinity immunoglobulin gamma Fc region receptor 2-b
Code
E3905Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.13ng/ml
Reactivity
Human
Detection range
0.13ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD32;CD32;CD32B;CDw32;FCG2;Fc-gamma RII-b;Fc-gamma-RIIb;FCGR2;FCGR2B;FCGR2C;FcRII-b;IGFR2;IgG Fc receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-b
