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Background
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
Product overview
Product Name
WD repeat- and FYVE domain-containing protein 4
Code
E6408Hu
Assay type
Sandwich
Size
96 test
Sensitivity
5.39ng/L
Reactivity
Human
Detection range
5.39ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
C10orf64;WD repeat- and FYVE domain-containing protein 4;WDFY4
