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Background
May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Product overview
Product Name
Radiation-inducible immediate-early gene IEX-1
Code
E6053Hu
Assay type
Sandwich
Size
96 test
Sensitivity
9.18ng/L
Reactivity
Human
Detection range
9.18ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
DIF2;DIF-2;Differentiation-dependent gene 2 protein;GLY96;IER3;IEX1;IEX-1;Immediate early protein GLY96;Immediate early response 3 protein;PACAP-responsive gene 1 protein;PRG1;Protein DIF-2;Protein PRG1;Radiation-inducible immediate-early gene IEX-1
