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Background
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
Product overview
Product Name
Mitochondrial fission 1 protein
Code
E6786Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.055ng/ml
Reactivity
Human
Detection range
0.055ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
CGI-135;FIS-1;FIS1 homolog;hFis1;Mitochondrial fission 1 protein;Tetratricopeptide repeat protein 11;TPR repeat protein 11;TTC11
