BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.
Background
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Product overview
Product Name
Tumor necrosis factor receptor superfamily member 10B
Code
E2536Mo
Assay type
Sandwich
Size
96 test
Sensitivity
0.124ng/mL
Reactivity
Mouse
Detection range
0.124ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD262;Death receptor 5;DR;DR5;KI;Kille;KILLER;Ly9;Ly98;MK;TNFRSF10B;TR;TRAILR2;TRIC;TRICK;TRICK2A;TRICK2B;TRICKB;Tumor necrosis factor receptor superfamily member 10B
