Home / Elisa Kits / BT LAB / Human Liver Carboxylesterase 1, CES1 ELISA Kit

Human Liver Carboxylesterase 1, CES1 ELISA Kit

Product Summary

Ordering Information

BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.

Background

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 18762277). Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester (PubMed: 7980644, PubMed: 9169443, PubMed: 9490062, PubMed: 18762277). Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine (PubMed: 7980644). Catalyzes the transesterification of cocaine to form cocaethylene (PubMed: 7980644). Displays fatty acid ethyl ester Synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate (PubMed: 7980644). Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins (PubMed: 21049984). Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process (PubMed: 18762277, PubMed: 16024911, PubMed: 11015575, PubMed: 16971496). First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile (PubMed: 18762277, PubMed: 18599737, PubMed: 16971496).

Product overview

Related Resources

Quotation request