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Background
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated Peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
Product overview
Product Name
Latent Transforming Growth Factor Beta Binding Protein 4
Code
E1815Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.024ng/ml
Reactivity
Human
Detection range
0.024ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
Latent-transforming growth factor beta-binding protein 4;LTBP 4;LTBP4;LTBP-4
