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Background
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). [Isoform 2]: Essential for the survival of colon cancer cells to bile acid-induced apoptosis.
Product overview
Product Name
Gastrotropin
Code
E5323Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.048ng/ml
Reactivity
Human
Detection range
0.048ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
FABP 6;FABP6;Fatty acid-binding protein 6;Gastrotropin;GT;I-15P;I-BABP;ILBP;Ileal lipid-binding protein;Intestinal 15 kDa protein;Intestinal bile acid-binding protein
