Human Fibroblast Growth Factor 2, FGF2 ELISA Kit

Product Summary

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BT LAB continuously updates its ELISA Kit catalog with the latest, validated products. If you’re unable to download a datasheet, please contact us to request the most recent version.

Background

Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed: 8663044). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed: 28302677). Binds to integrin ITGAV:ITGB3 (PubMed: 28302677). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed: 8663044, PubMed: 28302677). Functions as a potent mitogen in vitro (PubMed: 1721615, PubMed: 3964259, PubMed: 3732516). Can induce angiogenesis (PubMed: 23469107, PubMed: 28302677). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed: 29501879).

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