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Background
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 (PubMed: 30580966). Responsible for LAG3 T-cell inhibitory function (PubMed: 30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed: 30580966). Secreted by, and promotes growth of, hepatocytes (PubMed: 11470158, PubMed: 19880967).
Product overview
Product Name
Fibrinogen-Like Protein 1
Code
E3277Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.016ng/mL
Reactivity
Human
Detection range
0.016ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
FGL 1;FGL1;Fibrinogen-like protein 1;Hepassocin;Hepatocyte-derived fibrinogen-related protein 1;HFREP-1;HP-041;HPS;LFIRE-1;Liver fibrinogen-related protein 1