Human Cytochrome P450 2E1, CYP2E1 ELISA Kit

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Background

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed: 10553002, PubMed: 18577768). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH–hemoprotein reductase) (PubMed: 10553002, PubMed: 18577768). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed: 10553002, PubMed: 18577768). May be involved in the oxidative metabolism of xenobiotics (Probable).

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