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Background
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
Product overview
Product Name
Corticosteroid 11-Beta-Dehydrogenase Isozyme 2
Code
E6455Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.024ng/ml
Reactivity
Human
Detection range
0.024ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
11-beta-HSD;11-beta-HSD type II;11-beta-HSD2;11-beta-hydroxysteroid dehydrogenase type 2;11-beta-hydroxysteroid dehydrogenase type II;11-DH2;11-HSD type II;Corticosteroid 11-beta-dehydrogenase isozyme 2;HSD11B2;NAD-dependent 11-beta-hydroxysteroid dehydrogenase;Short chain dehydrogenase/reductase family 9C member 3