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Background
Cleaves the propeptides of type I and II collagen prior to fibril assembly (By similarity). Does not act on type III collagen (By similarity). Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form with reduced collagen-binding activity (PubMed: 31152061).
Product overview
Product Name
A Disintegrin and Metalloproteinase with Thrombospondin Motifs 2
Code
E3478Hu
Assay type
Sandwich
Size
96 test
Sensitivity
0.53ng/mL
Reactivity
Human
Detection range
0.53ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
A disintegrin and metalloproteinase with thrombospondin motifs 2;ADAMTS 2;ADAM-TS 2;ADAMTS2;ADAMTS-2;ADAM-TS2;PC I-NP;pNPI;Procollagen I N-proteinase;Procollagen I/II amino propeptide-processing enzyme;Procollagen N-endopeptidase