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Background
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Product overview
Product Name
Insulin Like Growth Factor Binding Protein 3
Code
E0017Bo
Assay type
Sandwich
Size
96 test
Sensitivity
0.24ng/ml
Reactivity
Bovine
Detection range
0.24ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
IBP-3;IGF-binding protein 3;IGFBP 3;IGFBP3;IGFBP-3;Insulin-like growth factor-binding protein 3