The Zymo-Spin I-96-XL Plate can be used in centrifuges for the large-scale (i.e., 96-well) purification of high molecular weight DNA and/or RNA. Its deep-well, durable polypropylene construction and unique silica-based matrix make it perfect for purifying up to 25 µg of DNA, or 50 µg of RNA, in ≥15 µl eluate per well. Capacity is 1.1 ml per well.