The Zymo-Spin IIC-XL column can be used either in microcentrifuges or on vacuum manifolds for the purification of high molecular weight DNA and/or RNA. The Zymo-Spin IIC-XL features durable polypropylene construction and contains a unique silica-based matrix that allows purification of up to 25 µg of DNA, and 50 µg of RNA, in ≥ 35 µl eluate. Capacity is 900 µl.