Multi-Mode Microplate Reader BL-B500

Multi-Mode Microplate Reader (BL-B500)

The Multi-Mode Series Microplate Reader is a versatile, high-performance system for absorbance, fluorescence, luminescence, fluorescence polarization, and time-resolved fluorescence detection. Designed for medical, biological, and pharmaceutical research, it combines reliable accuracy, modular upgrades, and intuitive software for advanced life science applications.

Highlights

✅ Multi-Detection Capability – Absorbance, fluorescence, luminescence, fluorescence polarization, and time-resolved fluorescence.
✅ Advanced Wavelength Range – 200–1000 nm via monochromator system.
✅ High Sensitivity & Stability – Optimized optical path, reference calibration, and PMT detection ensure accuracy.
✅ User-Friendly Design – 10-inch rotating touch screen with intuitive interface.
✅ Flexible Upgrades – Modular filter system, automatic injectors, and ultra-micro plate options.
✅ Efficient Data Handling – FTP transfer, advanced analysis algorithms, and customizable reporting.
✅ Wide Applications – Ideal for protein/nucleic acid quantification, receptor-ligand binding studies, kinase detection, hormone analysis, and viral marker detection.

Brand: Biolinkk

Product Overview

Description

The Multi-Mode Series Microplate Reader is a versatile, high-performance detection system designed for medical, biological, and pharmaceutical research and development institutions. Built to support diverse applications in drug development, molecular biology, biochemistry, and cytology, this system delivers high-quality, accurate, and reliable analysis.
Equipped with absorbance, fluorescence, and luminescence detection, it also supports advanced modes such as fluorescence polarization and time-resolved fluorescence. With a modular design, users can easily upgrade to additional functionalities like automatic injectors and u-Nano ultra-micro plate readers. Its optimized optical system ensures precision, while intuitive software and flexible data management simplify workflows.

Features

Optical & Detection System

Wavelength range: 200–1000 nm (monochromator-based).
Filter-based fluorescence detection with xenon lamp + PMT.
Time-resolved fluorescence with lanthanide dyes for high sensitivity.
Optimized optical path with fast polarizer switching to minimize deviation.

Modular Design & Upgrades

Modular Filter System – Quick replacement with QR-code scanning for accuracy.
MSS-2 Automatic Injector Block (optional) – With liquid injection protection.
u-Nano Ultra-Micro Plate Reader (optional) – Enables detection with only 2–4 µL sample volume.

Interface & Control

10-inch Rotating Touchscreen with adjustable viewing angle.
Intuitive software with user authority classification for secure access.
Independent storage of programs and results for streamlined workflows.

Data Analysis & Management

Built-in software supports:
FTP Transfer Protocol – Seamless data upload to authorized computers.
Independent PC analysis software (optional) for deeper reporting and algorithm-based results.

Performance & Reliability

Automatic calibration of light source, detector, monochromator, and position for stable operation.

Reference optical path ensures long-term stability of detection data.

Robust design for high-throughput nucleic acid and protein quantification.

Specifications

Technical Parameter

Model	BL-B500
Absorbance
Light source	Xenon lamp
Detector	PD
Wavelength accuracy	2 nm
Wavelength repeatability (SD)	0.2 nm
Half width (FWHM)	<2.5 nm
Wavelength range	200-1000 nm, 1 nm step
Measure range	0-4 OD
Resolution	0.0001 OD
Accuracy @450 nm	96-precision mode: ± (1.0 %+0.003 Abs) @ (0.0-2.0 Abs] ±2.0 % @ (2.0-3.0 Abs]
Repeatability @450 nm	CV <1.0 % or SD <0.003 fast (0.0-3.0Abs] CV <0.5 % or SD <0.003 accurate (0.0-3.0Abs]
Stray light	0.1% @220 nm
Linear @450 nm	R2 >0.999 @ [0.0 – 3.0 Abs]
Reading time	96-well plate: fast <15 s
Luminescence
Detector	PMT
Detection limit	15 amol / well; 5 amol / well (photon PMT)
Linear dynamic range	6 logs
Crosstalk	<0.005 %
Wavelength range	200-850 nm
Fluorescence
Reading mode	Top reading
Excitation light source	Xenon lamp
Detector	PMT
Wavelength range	EX: 200-1000 nm; EM: 270-850 nm
Filter EX / EM	3 groups: EX470 / EM525, EX523 / EM564, EX624 / EM692 (other wavelengths can be replaced)
Detection limit	1 pM
Linear dynamic range	6 logs
TRF
Wavelength range	—
Detection limit	0.05 pM
FP
Wavelength range	300 – 850 nm
Detection limit	5 mP

Basic Parameter

Model	BL-B500
Plate	6-384 well
Accessories	Microplate, injector
Shaking mode	Linear, annular, double annular
Incubation temperature	RT. +4 °C ~ 45 °C
Temperature uniformity	±0.5 °C @ 37 °C
Software interface	Chinese / English
Screen size	10-inch
Operation method	Capacitive screen touch, mouse
Data capacity	10 GB
Compatibility	Support PC software, Win7 / Win 10 64 bit
Network transmission	The test data report can be uploaded to the PC server through FTP
Instrument port	2 USB Type A ports, 1 USB Type B port, 1 Ethernet port, Rs232 bus interface (connected to the injector)
Power supply	AC 100-240 V, 50-60 Hz
Dimension (WxDxH)	420x550x386 mm
Weight	33 kg

Documents

Additional Info

Accessory Parameter

Microplate
Sample number	1-16
Sample detection volume	2-4 pL
Automatic Injector
Quantity	1 / 2
Dispensing volume	5-1000 pL, 1 pL increment
Liquid injection speed	125-500 pL/s
Accuracy	±1 pL @ 5-50 pL; ±2 % @ 51-1000 pL
Waste liquid collection	50 mL
Software
Analysis software	Readerlt-ll software

Ordering Information

BL-B300 microplate reader (multi-mode)

BL-B400 microplate reader (multi-mode)

BL-B500 microplate reader (multi-mode)

Readerlt-ll PC analysis software

u-Nano ultra-micro plate

ABS optical performance validation board

MSS-2 automatic injector