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Background
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Product overview
Product Name
Vascular cell adhesion protein 1
Code
E2318Ra
Assay type
Sandwich
Size
96 test
Sensitivity
3.04ng/mL
Reactivity
Rat
Detection range
3.04ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
CD antigen CD106;Vascular cell adhesion protein 1;V-CAM 1;VCAM-1;VCAM1B
