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Background
Transgelin is a protein that in humans is encoded by the TAGLN gene. The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
Product overview
Product Name
Transgelin
Code
E2289Ra
Assay type
Sandwich
Size
96 test
Sensitivity
0.055ng/mL
Reactivity
Rat
Detection range
0.055ng/mL
Sample type
Serum, plasma, cell culture supernates
Synonyms
Sm22;SM22-alpha;Smooth muscle protein 22-alpha;TAGLN;Transgelin