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Background
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
Product overview
Product Name
Growth/Differentiation Factor 11
Code
E1998Ra
Assay type
Sandwich
Size
96 test
Sensitivity
4.54ng/L
Reactivity
Rat
Detection range
4.54ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
BMP-11;Bone morphogenetic protein 11;GDF 11;GDF11;GDF-11;Growth/differentiation factor 11
