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Background
Cleaves aggrecan, a cartilage proteoglycan, at the ‘1683-Glu-|-Leu-1684’ site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Has angiogenic inhibitor activity (By similarity).
Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture (By similarity).
Product overview
Product Name
Adisintegrin and metalloproteinase with thrombospondin motifs 12
Code
E1724Ra
Assay type
Sandwich
Size
96 test
Sensitivity
0.32ng/ml
Reactivity
Rat
Detection range
0.32ng/ml
Sample type
Serum, plasma, cell culture supernates
Synonyms
A disintegrin and metalloproteinase with thrombospondin motifs 1;ADAM-TS 1;ADAMTS-1;ADAM-TS1;ADAMTS12
