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Background
Interacts with centromeric heterochromatin in chromosomes and binds to a specific 17 bp subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher-order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
Product overview
Product Name
Major Centromere Autoantigen B
Code
E2232Mo
Assay type
Sandwich
Size
96 test
Sensitivity
7.45ng/L
Reactivity
Mouse
Detection range
7.45ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
CENPB;CENP-B;Centromere protein B;Major centromere autoantigen B