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Background
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3′-untranslated regions (3′-UTRs) of stress-responsive transcripts RPA2 and TXN.
Product overview
Product Name
Cold-inducible RNA-binding protein
Code
E1951Mo
Assay type
Sandwich
Size
96 test
Sensitivity
2.24ng/L
Reactivity
Mouse
Detection range
2.24ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
A18 hnRNP;CIRBP;Cirp;Cold-inducible RNA-binding protein;Glycine-rich RNA-binding protein CIRP;R74941
