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Background
Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
Product overview
Product Name
Beta-Klotho
Code
E1880Mo
Assay type
Sandwich
Size
96 test
Sensitivity
9.74ng/L
Reactivity
Mouse
Detection range
9.74ng/L
Sample type
Serum, plasma, cell culture supernates
Synonyms
BetaKlotho;Beta-klotho;BKL;KLB;Klotho beta-like protein
